Applying human cell and regenerative medicine technologies to efficacy and safety testing of new drugs
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Precision Medicine: A New Revolution in Healthcare System
Every human being is different based on genetics, lifestyle, and environmental factors. Novel medical technologies have become more precise owing to molecular information, including genomics, transcriptomics, proteomics, metabolomics, etc. The “omics” technologies have opened up new horizons for healthcare systems, enabling them to prevent and/or diagnose diseases more precisel...
متن کاملBio-printing Damaged Tissues: A Novel Approach in Regenerative Medicine
Regenerative medicine, deals with functional reconstruction of damaged tissues or organs after severe injuries chronic diseases, while body's natural responses are not sufficient. In this field, stem cells due to their exclusive potential in self-renewal and differentiation into other cell types, are the main sources of functional cells in regenerative medicine. However, challenges in stem cell...
متن کاملDental Residents’ Knowledge and Attitude towards Stem Cells and Regenerative Dentistry
Objectives: Success of regenerative dental procedures highly depends on their acceptance by the clinicians; yet, little is known about dental residents’ attitudes regarding this new technology. The purpose of this study was to assess the knowledge and attitude of post-graduate dental students towards stem cells and regenerative dentistry as part of future dental treatments. Methods: This cross...
متن کاملINVESTIGATION ON THE SAFETY OF AMNIOTIC MEMBRANE EXTRACTS IN IMPROVING DIABETIC FOOT ULCERS (PHASE 1 CLINICAL TRIAL STUDY)
Background: For nearly 100 years, amniotic membranes have been used to treat various types of skin wounds. Amniotic extract is one of the derivatives of amniotic membrane that contains all the properties of amniotic membrane. The aim of this study was to evaluate the safety of the amniotic membrane extract in the treatment of diabetic ulcers. Methods: This study was an Open labeled clinical tr...
متن کاملBiological characteristics of Stem Cells from Human Exfoliated Deciduous Teeth (SHEDs) and its therapeutic applications in regenerative medicine
Stem cells isolated from human exfoliated deciduous teeth (SHEDs) are multipotent mesenchymal stem cells that are isolated from dental pulp tissues. These cells have a high proliferative capacity, multipotential ability, immunomodulatory function, and minimal risk of oncogenesis. Recent studies have shown that SHEDs are a feasible cell source for cell therapy and regenerative medicine.
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